Follicle-Stimulating Hormone-Independent Functions of Primate Sertoli Cells: Potential Implications in the Diagnosis and Management of Male Infertility | Zendy

Y. Sangeeta Devi | Zendy; Kanchan Sarda | Zendy; Benjamin Stephen | Zendy; Perumal Nagarajan | Zendy; Subeer S. Majumdar | Zendy

Open Access

Follicle-Stimulating Hormone-Independent Functions of Primate Sertoli Cells: Potential Implications in the Diagnosis and Management of Male Infertility

Author(s) -

Y. Sangeeta Devi,

Kanchan Sarda,

Benjamin Stephen,

Perumal Nagarajan,

Subeer S. Majumdar

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-2072

Subject(s) - endocrinology , medicine , sertoli cell , biology , testosterone (patch) , gonadotropin , follicle stimulating hormone , context (archaeology) , primate , spermatogenesis , hormone , luteinizing hormone , neuroscience , paleontology

FSH is known to augment the production of essential germ cell (Gc) survival factors, lactate and estradiol, by Sertoli cells (Sc) of 18-d-old pubertal rats. However, the failure of gonadotropin and androgen treatment to initiate spermatogenesis in testis of some infertile men bearing Sc and Gc is intriguing. The role of FSH in regulation of lactate and estradiol production by primate Sc is currently unknown.

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