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Gestational Age-Dependent Up-Regulation of Prostaglandin D Synthase (PGDS) and Production of PGDS-Derived Antiinflammatory Prostaglandins in Human Placenta
Author(s) -
Rachel J. A. Helliwell,
Jeffrey A. Keelan,
Keith W. Marvin,
Linda F. Adams,
Maxwell C. Chang,
Ashmit Anand,
Timothy A. Sato,
Simon J. O’Carroll,
Tinnakorn Chaiworapongsa,
Roberto Romero,
Murray D. Mitchell
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2005-1982
Subject(s) - context (archaeology) , placenta , prostaglandin , mechanism (biology) , prostaglandin f , pregnancy , pathological , endocrinology , atp synthase , prostaglandin e2 receptor , medicine , prostaglandin e , chemistry , microbiology and biotechnology , biology , fetus , biochemistry , enzyme , receptor , paleontology , philosophy , genetics , epistemology , agonist
The importance of prostaglandin (PG) signaling pathways to the maintenance of pregnancy and initiation of labor is well recognized. However, the complexity of these pathways and the mechanism(s) of their coordinated regulation in physiological and pathological conditions are only now being appreciated.

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