Tumor Necrosis Factor α and Glucocorticoid Synergistically Increase Leptin Production in Human Adipose Tissue: Role for p38 Mitogen-Activated Protein Kinase | Zendy

Maria E. Trujillo | Zendy; MiJeong Lee | Zendy; Sean Sullivan | Zendy; Jianying Feng | Zendy; Stephen H. Schneider | Zendy; Andrew S. Greenberg | Zendy; Susan K. Fried | Zendy

Open Access

Tumor Necrosis Factor α and Glucocorticoid Synergistically Increase Leptin Production in Human Adipose Tissue: Role for p38 Mitogen-Activated Protein Kinase

Author(s) -

Maria E. Trujillo,

MiJeong Lee,

Sean Sullivan,

Jianying Feng,

Stephen H. Schneider,

Andrew S. Greenberg,

Susan K. Fried

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-1901

Subject(s) - adipose tissue , leptin , p38 mitogen activated protein kinases , protein kinase a , mitogen activated protein kinase , tumor necrosis factor alpha , cancer research , glucocorticoid , medicine , kinase , endocrinology , microbiology and biotechnology , biology , obesity

TNF increases plasma leptin in humans in vivo, but previous studies showed it decreases leptin in vitro.

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