Elevated Peptide YY Levels in Adolescent Girls with Anorexia Nervosa | Zendy

Madhusmita Misra | Zendy; Karen K. Miller | Zendy; Patrika Tsai | Zendy; Katie M. Gallagher | Zendy; Alvin C. Lin | Zendy; Noel Lee | Zendy; David B. Herzog | Zendy; Anne Klibanski | Zendy

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Elevated Peptide YY Levels in Adolescent Girls with Anorexia Nervosa

Author(s) -

Madhusmita Misra,

Karen K. Miller,

Patrika Tsai,

Katie M. Gallagher,

Alvin C. Lin,

Noel Lee,

David B. Herzog,

Anne Klibanski

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-1878

Subject(s) - endocrinology , medicine , peptide yy , ghrelin , leptin , body mass index , osteocalcin , anorexia nervosa , chemistry , hormone , receptor , obesity , eating disorders , neuropeptide y receptor , neuropeptide , biochemistry , alkaline phosphatase , enzyme , psychiatry

Peptide YY (PYY) is an intestinally derived anorexigen that acts via the Y2 receptor, and Y2 receptor deletion in rodents increases bone formation. Anorexia nervosa (AN) is associated with a deliberate reduction in food intake and low bone density, but endocrine modulators of food intake in AN are not known. In addition, known regulators of bone turnover, such as GH, cortisol, and estrogen, explain only a fraction of the variability in bone turnover marker levels.

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