Serum γ-Glutamyl Transpeptidase Is a Determinant of Insulin Resistance Independently of Adiposity in Pima Indian Children | Zendy

Emilio Ortega | Zendy; Juraj Koška | Zendy; Arline D. Salbe | Zendy; P. Antonio Tataranni | Zendy; Joy C. Bunt | Zendy

Open Access

Serum γ-Glutamyl Transpeptidase Is a Determinant of Insulin Resistance Independently of Adiposity in Pima Indian Children

Author(s) -

Emilio Ortega,

Juraj Koška,

Arline D. Salbe,

P. Antonio Tataranni,

Joy C. Bunt

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-1783

Subject(s) - medicine , insulin resistance , endocrinology , body mass index , obesity , context (archaeology) , alanine aminotransferase , insulin , homeostasis , gamma glutamyltransferase , diabetes mellitus , enzyme , biology , biochemistry , paleontology

Elevated activities of serum enzymes, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyltransferase (GGT), have been associated with obesity and insulin resistance (IR). ALT is an independent predictor of type 2 diabetes mellitus (T2DM) in adult Pima Indians, and GGT predicts T2DM in other adult populations.

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