Final Height in Girls with Central Idiopathic Precocious Puberty Treated with Gonadotropin-Releasing Hormone Analog and Oxandrolone
Author(s) -
Alessandra Vottero,
Simona Pedori,
Marta Verna,
Blandina Pagano,
Marco Cappa,
Sandro Loche,
Sergio Bernasconi,
Lucia Ghizzoni
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2005-1693
Subject(s) - oxandrolone , medicine , triptorelin , endocrinology , bone age , testosterone (patch) , growth hormone , gonadotropin , gonadotropin releasing hormone , hormone , luteinizing hormone
GnRH analogs (GnRHa) are considered the treatment of choice for central precocious puberty (CPP). During GnRHa administration, the suppression of the pituitary-gonadal axis results in decreased rates of linear growth and skeletal maturation and in improved adult height. However, in some patients, the growth deceleration is so marked that the expected improvement in predicted adult height is not achieved.
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