Type 1 Diabetes-Associated Autoimmunity: Natural History, Genetic Associations, and Screening | Zendy

Jennifer M. Barker | Zendy

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Type 1 Diabetes-Associated Autoimmunity: Natural History, Genetic Associations, and Screening

Author(s) -

Jennifer M. Barker

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-1679

Subject(s) - ptpn22 , immunology , major histocompatibility complex , autoimmunity , autoimmune disease , human leukocyte antigen , type 1 diabetes , autoantibody , medicine , context (archaeology) , biology , genetics , antigen , diabetes mellitus , endocrinology , gene , genotype , immune system , single nucleotide polymorphism , antibody , paleontology

Type 1 diabetes (T1D) is associated with autoimmune thyroid disease (AIT), celiac disease (CD), Addison's disease (AD), and other autoimmune diseases. These diseases can occur together in defined syndromes with distinct pathophysiology and characteristics: autoimmune polyendocrine syndrome I, autoimmune polyendocrine syndrome II, and the immunodysregulation polyendocrinopathy enteropathy X-linked syndrome.

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