Weight Loss Reduces Adipose Tissue Cathepsin S and Its Circulating Levels in Morbidly Obese Women
Author(s) -
Soraya Taleb,
Raffaella Cancello,
Christine Poitou,
Christine Rouault,
Philippe Sellam,
Patrick Lévy,
Jean-Luc Bouillot,
Christiane Coussieu,
Arnaud Basdevant,
Michèle Guerre-Millo,
Danièle Lacasa,
Karine Clément
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2005-1601
Subject(s) - adipose tissue , white adipose tissue , adipokine , endocrinology , context (archaeology) , medicine , cathepsin s , pathogenesis , cathepsin , morbidly obese , leptin , biology , obesity , weight loss , enzyme , biochemistry , paleontology
Human adipose tissue produces several adipokines, including the newly identified protein cathepsin S (CTSS), a cysteine protease involved in the pathogenesis of atherosclerosis. Obesity is characterized by high levels of CTSS in the circulation and in sc white adipose tissue (scWAT).
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