The d3-Growth Hormone (GH) Receptor Polymorphism Is Associated with Increased Responsiveness to GH in Turner Syndrome and Short Small-for-Gestational-Age Children | Zendy

Gerhard Binder | Zendy; Friederike Baur | Zendy; Roland Schweizer | Zendy; Michael B. Ranke | Zendy

Open Access

The d3-Growth Hormone (GH) Receptor Polymorphism Is Associated with Increased Responsiveness to GH in Turner Syndrome and Short Small-for-Gestational-Age Children

Author(s) -

Gerhard Binder,

Friederike Baur,

Roland Schweizer,

Michael B. Ranke

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-1581

Subject(s) - medicine , turner syndrome , endocrinology , small for gestational age , growth hormone receptor , gestational age , growth hormone , hormone , pregnancy , biology , genetics

A protein polymorphism of the GH receptor (GHR) based on the genomic deletion of exon 3 (d3-GHR) has recently been linked to the magnitude of growth response to high-dose recombinant human GH (rhGH) therapy of short children without GH deficiency.

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