Inhibition of Estrogen Biosynthesis with a Potent Aromatase Inhibitor Increases Predicted Adult Height in Boys with Idiopathic Short Stature: A Randomized Controlled Trial | Zendy

Matti Hero | Zendy; Ensio Norjavaara | Zendy; Leo Dunkel | Zendy

Open Access

Inhibition of Estrogen Biosynthesis with a Potent Aromatase Inhibitor Increases Predicted Adult Height in Boys with Idiopathic Short Stature: A Randomized Controlled Trial

Author(s) -

Matti Hero,

Ensio Norjavaara,

Leo Dunkel

Publication year - 2005

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-1392

Subject(s) - estrogen , endocrinology , aromatase , medicine , context (archaeology) , idiopathic short stature , randomized controlled trial , aromatase inhibitor , short stature , biology , growth hormone , hormone , cancer , breast cancer , paleontology

In males as well as in females, estrogen is an essential regulator of bone maturation, growth plate fusion, and cessation of longitudinal growth. Therefore, an increase in predicted adult height (PAH) may be achieved in short boys by blocking estrogen biosynthesis.

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