1,25-Dihydroxyvitamin D Suppresses Circulating Levels of Parathyroid Hormone in a Patient with Primary Hyperparathyroidism and Coexistent Sarcoidosis | Zendy

Yuka Kinoshita | Zendy; Manabu Taguchi | Zendy; Akira Takeshita | Zendy; Daishu Miura | Zendy; Shinji Tomikawa | Zendy; Yasuhiro Takeuchi | Zendy

Open Access

1,25-Dihydroxyvitamin D Suppresses Circulating Levels of Parathyroid Hormone in a Patient with Primary Hyperparathyroidism and Coexistent Sarcoidosis

Author(s) -

Yuka Kinoshita,

Manabu Taguchi,

Akira Takeshita,

Daishu Miura,

Shinji Tomikawa,

Yasuhiro Takeuchi

Publication year - 2005

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-1380

Subject(s) - medicine , endocrinology , parathyroid hormone , primary hyperparathyroidism , hyperparathyroidism , context (archaeology) , sarcoidosis , chemistry , biology , calcium , paleontology

PTH is excessively secreted to develop hypercalcemia and accelerate bone turnover in patients with primary hyperparathyroidism. PTH stimulates the production of 1,25-dihydroxyvitamin D [1,25(OH)2D] that in turn suppresses the synthesis of PTH in parathyroid cells.

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