Increased Thyroxine Sulfate Levels in Critically Ill Patients as a Result of a Decreased Hepatic Type I Deiodinase Activity | Zendy

Robin P. Peeters | Zendy; Monique H. A. Kester | Zendy; Pieter Wouters | Zendy; Ellen Kaptein | Zendy; Hans van Toor | Zendy; Theo J. Visser | Zendy; Greet Van den Berghe | Zendy

Open Access

Increased Thyroxine Sulfate Levels in Critically Ill Patients as a Result of a Decreased Hepatic Type I Deiodinase Activity

Author(s) -

Robin P. Peeters,

Monique H. A. Kester,

Pieter Wouters,

Ellen Kaptein,

Hans van Toor,

Theo J. Visser,

Greet Van den Berghe

Publication year - 2005

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-0866

Subject(s) - medicine , endocrinology , deiodinase , chemistry , hormone , thyroid hormones

Marked changes in peripheral thyroid hormone metabolism occur in critical illness, resulting in low serum T3 and high rT3 levels. In this study, we investigated whether T4S levels are increased in patients who died after intensive care and whether T4S levels are correlated with liver type I deiodinase (D1) or sulfotransferase (SULT) activity.

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