Nuclear Receptor Coactivator-3 Alleles Are Associated with Serum Bioavailable Testosterone, Insulin-Like Growth Factor-1, and Vertebral Bone Mass in Men
Author(s) -
Yahtyng Sheu,
Joseph M. Zmuda,
Jane A. Cauley,
Susan P Moffett,
Clifford J. Rosen,
Chandra Ishwad,
Robert E. Ferrell
Publication year - 2006
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2005-0864
Subject(s) - endocrinology , medicine , allele , igfbp3 , biology , genotype , nuclear receptor coactivator 3 , bone mineral , androgen receptor , osteoporosis , coactivator , receptor , genetics , growth factor , gene , prostate cancer , cancer , transcription factor
Nuclear receptor coactivator-3 (NCOA3) is a member of the steroid receptor coactivator family that interacts with nuclear hormone receptors to enhance their transcriptional activation function and may play a role in somatic growth.
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