Expression Profiles for Steroidogenic Enzymes in Adrenocortical Disease
Author(s) -
Mary H. Bassett,
Bobbie Mayhew,
Khurram Rehman,
Perrin C. White,
Franco Mantero,
Giorgio Arnaldi,
Paul M. Stewart,
Iwona Bujalska,
William E. Rainey
Publication year - 2005
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2005-0836
Subject(s) - aldosterone , context (archaeology) , endocrinology , medicine , adenoma , adrenocortical adenoma , hydrocortisone , adrenal cortex , biology , paleontology
Excess production of aldosterone or cortisol has profound effects on cardiovascular function and impacts other major organ systems. The mechanisms leading to the autonomous hypersecretion of aldosterone or cortisol in aldosterone-producing adenoma (APA) or cortisol-producing adenoma (CPA) are unknown.
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