Response of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases Messenger Ribonucleic Acids to Ovarian Steroids in Human Endometrial Explants Mimics Their Gene- and Phase-Specific Differential Controlin Vivo | Zendy

Vassil Vassilev | Zendy; Chrystel Pretto | Zendy; Patricia B. Cornet | Zendy; Denis Delvaux | Zendy; Yves Eeckhout | Zendy; Pierre J. Courtoy | Zendy; Étienne Marbaix | Zendy; Patrick Henriet | Zendy

Open Access

Response of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases Messenger Ribonucleic Acids to Ovarian Steroids in Human Endometrial Explants Mimics Their Gene- and Phase-Specific Differential Controlin Vivo

Author(s) -

Vassil Vassilev,

Chrystel Pretto,

Patricia B. Cornet,

Denis Delvaux,

Yves Eeckhout,

Pierre J. Courtoy,

Étienne Marbaix,

Patrick Henriet

Publication year - 2005

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-0762

Subject(s) - matrix metalloproteinase , endometrium , in vivo , endocrinology , medicine , biology , extracellular matrix , ovary , hormone , andrology , chemistry , microbiology and biotechnology

Cyclic remodeling and breakdown of the extracellular matrix, a unique feature of the human endometrium, depends on matrix metalloproteinases (MMPs). These enzymes are globally controlled by estradiol and progesterone or their withdrawal, but various MMPs and their tissue inhibitors (TIMPs) show distinct responses.

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