A Genome-Wide Screen in 1119 Relative Pairs with Autoimmune Thyroid Disease | Zendy

Jenny C. Taylor | Zendy; Stephen Gough | Zendy; P. J. Hunt | Zendy; Thomas Heiberg Brix | Zendy; Krishna Chatterjee | Zendy; J. M. C. Connell | Zendy; J. A. Franklyn | Zendy; László Hegedűs | Zendy; Bruce G. Robinson | Zendy; W. M. Wiersinga | Zendy; J. A. H. Wass | Zendy; Delilah Zabaneh | Zendy; Ian R. Mackay | Zendy; A. P. Weetman | Zendy

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A Genome-Wide Screen in 1119 Relative Pairs with Autoimmune Thyroid Disease

Author(s) -

Jenny C. Taylor,

Stephen Gough,

P. J. Hunt,

Thomas Heiberg Brix,

Krishna Chatterjee,

J. M. C. Connell,

J. A. Franklyn,

László Hegedűs,

Bruce G. Robinson,

W. M. Wiersinga,

J. A. H. Wass,

Delilah Zabaneh,

Ian R. Mackay,

A. P. Weetman

Publication year - 2006

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2005-0686

Subject(s) - autoimmune disease , graves' disease , thyroid , genome , disease , thyroid disease , medicine , biology , immunology , genetics , gene

Autoimmune thyroid diseases (AITD), comprising Graves' disease and autoimmune hypothyroidism, are characterized by loss of immunological self-tolerance to thyroid antigens. These are complex diseases arising from a combination of genetic and environmental factors. An understanding of the genetic susceptibility factors for AITD could help to target treatments more effectively and identify people at risk for these conditions.

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