Glucose Homeostasis and Safety in Patients with Acromegaly Converted from Long-Acting Octreotide to Pegvisomant
Author(s) -
Ariel L. Barkan,
Pia Burman,
David R. Clemmons,
William Drake,
Robert F. Gagel,
Philip E. Harris,
Peter Trainer,
Aart Jan van der Lely,
Mary Lee Vance
Publication year - 2005
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2005-0331
Subject(s) - pegvisomant , acromegaly , medicine , octreotide , endocrinology , glycemic , diabetes mellitus , glucose homeostasis , somatostatin , population , liter , glucose clamp technique , insulin resistance , pancreatic hormone , hormone , growth hormone , environmental health
In clinical practice, patients with acromegaly may be switched from therapy with long-acting somatostatin analogs to pegvisomant. The effect of changing therapies on glucose homeostasis and safety has not been reported.
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