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Management of Graves’ Disease during Pregnancy: The Key Role of Fetal Thyroid Gland Monitoring
Author(s) -
Dominique Luton,
Isabelle Le Gac,
Edith Vuillard,
Mireille Castanet,
Jean Guibourdenche,
Michèle Noël,
MarieElisabeth Toubert,
Juliane Léger,
C. Boissinot,
MarieHélène Schlageter,
Cathérine Garel,
Brigitte Tébeka,
JeanFrançois Oury,
Paul Czernichow,
Michel Polak
Publication year - 2005
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2004-2555
Subject(s) - medicine , thyroid , fetus , euthyroid , pregnancy , thyroid function , thyroid function tests , gestation , endocrinology , thyroid disease , obstetrics , genetics , biology
Fetuses from mothers with Graves' disease may experience hypothyroidism or hyperthyroidism due to transplacental transfer of antithyroid drugs (ATD) or anti-TSH receptor antibodies, respectively. Little is known about the fetal consequences. Early diagnosis is essential to successful management. We investigated a new approach to the fetal diagnosis of thyroid dysfunction and validated the usefulness of fetal thyroid ultrasonograms.

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