Sex-Related Differences in Stimulated Hypothalamic-Pituitary-Adrenal Axis during Induced Gonadal Suppression
Author(s) -
Karen Putnam,
George P. Chrousos,
Lynnette K. Nieman,
David R. Rubinow
Publication year - 2005
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2004-2525
Subject(s) - medicine , endocrinology , analysis of variance , testosterone (patch) , stressor , stimulation , hypothalamic–pituitary–adrenal axis , repeated measures design , hypothalamic–pituitary–gonadal axis , sex characteristics , psychology , physiology , hormone , luteinizing hormone , clinical psychology , statistics , mathematics
Sex-related differences in the stress response are well described in the animal literature but in humans are inconsistent and appear to reflect both the method used to stimulate the hypothalamic-pituitary-adrenal (HPA) axis and the age of the subjects. Sex-related differences in reproductive steroid levels further confound efforts to define the specific role of the sex of the individual in stress axis responsivity.
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