Liver Fat and Insulin Resistance Are Independently Associated with the −514C>T Polymorphism of the Hepatic Lipase Gene | Zendy

Norbert Stefan | Zendy; Silke Schäfer | Zendy; Fausto Machicao | Zendy; Jürgen Machann | Zendy; Fritz Schick | Zendy; Claus D. Claussen | Zendy; Michael Stümvoll | Zendy; HansUlrich Häring | Zendy; Andreas Fritsche | Zendy

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Liver Fat and Insulin Resistance Are Independently Associated with the −514C>T Polymorphism of the Hepatic Lipase Gene

Author(s) -

Norbert Stefan,

Silke Schäfer,

Fausto Machicao,

Jürgen Machann,

Fritz Schick,

Claus D. Claussen,

Michael Stümvoll,

HansUlrich Häring,

Andreas Fritsche

Publication year - 2005

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2004-2479

Subject(s) - medicine , endocrinology , insulin resistance , hepatic lipase , insulin , biology , adipose tissue , genotype , lipase , adiponectin , gene polymorphism , lipoprotein lipase , gene , enzyme , biochemistry

Liver fat predicts insulin resistance in humans. So far, there is not much information on genetic determinants of liver fat. Hepatic lipase is a liver-specific enzyme that regulates lipid metabolism.

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