Dramatic Elevations of Interleukin-6 and Acute-Phase Reactants in Athletes Participating in the Ultradistance Foot Race Spartathlon: Severe Systemic Inflammation and Lipid and Lipoprotein Changes in Protracted Exercise | Zendy

Alexandra Margeli | Zendy; Katerina Skenderi | Zendy; Maria Tsironi | Zendy; Eugenia Hantzi | Zendy; AntoniaLeda Matalas | Zendy; Christina Vrettou | Zendy; Emmanuel Kanavakis | Zendy; George P. Chrousos | Zendy; Ioannis Papassotiriou | Zendy

Open Access

Dramatic Elevations of Interleukin-6 and Acute-Phase Reactants in Athletes Participating in the Ultradistance Foot Race Spartathlon: Severe Systemic Inflammation and Lipid and Lipoprotein Changes in Protracted Exercise

Author(s) -

Alexandra Margeli,

Katerina Skenderi,

Maria Tsironi,

Eugenia Hantzi,

AntoniaLeda Matalas,

Christina Vrettou,

Emmanuel Kanavakis,

George P. Chrousos,

Ioannis Papassotiriou

Publication year - 2005

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2004-2346

Subject(s) - medicine , apolipoprotein b , endocrinology , serum amyloid a , acute phase protein , c reactive protein , lipoprotein , inflammation , athletes , interleukin 6 , cholesterol , physical therapy

Plasma IL-6, the serum inflammatory markers C-reactive protein (CRP) and serum amyloid A (SAA), and the tissue destruction marker-free plasma DNA, as well as the circulating lipid profile, were examined in athletes participating in the ultradistance foot race of the 246-km Spartathlon. SETTING, DESIGN, AND PARTICIPANTS: This race consists of continuous, prolonged, brisk exercise. Blood samples were obtained from 15 male athletes, who finished the race in less than 36 h, taken before, at the end of, and 48 h after the end of the race.

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