A Common Single Nucleotide Polymorphism in Exon 10 of the Human Follicle Stimulating Hormone Receptor Is a Major Determinant of Length and Hormonal Dynamics of the Menstrual Cycle | Zendy

R. R. Greb | Zendy; K Grieshaber | Zendy; Jörg Gromoll | Zendy; Barbara Sonntag | Zendy; Eberhard Nieschlag | Zendy; Ludwig Kiesel | Zendy; Manuela Simoni | Zendy

Open Access

A Common Single Nucleotide Polymorphism in Exon 10 of the Human Follicle Stimulating Hormone Receptor Is a Major Determinant of Length and Hormonal Dynamics of the Menstrual Cycle

Author(s) -

R. R. Greb,

K Grieshaber,

Jörg Gromoll,

Barbara Sonntag,

Eberhard Nieschlag,

Ludwig Kiesel,

Manuela Simoni

Publication year - 2005

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2004-2268

Subject(s) - endocrinology , medicine , ovulation , follicular phase , menstrual cycle , luteal phase , follicle stimulating hormone , biology , hormone , follicle stimulating hormone receptor , luteinizing hormone

FSH is essential for follicular maturation. Data from ovarian hyperstimulation cycles suggest that FSH action is attenuated by a frequent single nucleotide polymorphism of the FSH receptor gene exchanging Asn for Ser at codon 680.

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