Open AccessA Twin Study for Serum Leptin, Soluble Leptin Receptor, and Free Insulin-Like Growth Factor-I in Pubertal Females
Author(s) -
Hongjuan Li,
Cheng-ye Ji,
Wei Wang,
Yonghua Hu
Publication year - 2005
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2004-2079
Subject(s) - leptin , endocrinology , medicine , leptin receptor , context (archaeology) , hypothalamus , insulin , receptor , biology , insulin like growth factor , growth factor , obesity , paleontology
Leptin and IGF-I are two peripheral metabolic signals linking body energy status to hypothalamus GnRH generator and involved in the pubertal development and metabolic disorders. The changes of their biological activity through puberty and the genetic basis are not clear.
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