A Polymorphism Exon 1 Variant at the Locus of the Scavenger Receptor Class B Type I (SCARB1) Gene Is Associated with Differences in Insulin Sensitivity in Healthy People during the Consumption of an Olive Oil-Rich Diet | Zendy

Pablo PérezMartínez | Zendy; Francisco PérezJiménez | Zendy; C. Bellido | Zendy; José M. Ordovás | Zendy; Juan Antonio Moreno | Zendy; Carmen Marı́n | Zendy; Purificación Gómez | Zendy; Javier DelgadoLista | Zendy; Francisco Fuentes | Zendy; José LópezMiranda | Zendy

Open Access

A Polymorphism Exon 1 Variant at the Locus of the Scavenger Receptor Class B Type I (SCARB1) Gene Is Associated with Differences in Insulin Sensitivity in Healthy People during the Consumption of an Olive Oil-Rich Diet

Author(s) -

Pablo PérezMartínez,

Francisco PérezJiménez,

C. Bellido,

José M. Ordovás,

Juan Antonio Moreno,

Carmen Marı́n,

Purificación Gómez,

Javier DelgadoLista,

Francisco Fuentes,

José LópezMiranda

Publication year - 2005

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2004-1489

Subject(s) - scavenger receptor , endocrinology , medicine , type 2 diabetes , insulin , crossover study , exon , genotype , fatty acid , biology , cholesterol , lipoprotein , diabetes mellitus , biochemistry , gene , placebo , alternative medicine , pathology

Scavenger receptor class B type I (SCARB1) was described as the first high-density lipoprotein receptor. Increasing evidence indicates that SCARB1 plays additional roles particularly in type 2 diabetes mellitus. Our aim was to determine whether the presence of an exon 1 (G-->A) polymorphism at the SCARB1 gene modifies the insulin sensitivity to dietary fat.

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