Assessment of Insulin Sensitivity from Measurements in the Fasting State and during an Oral Glucose Tolerance Test in Polycystic Ovary Syndrome and Menopausal Patients | Zendy

Mario Ciampelli | Zendy; Fulvio Leoni | Zendy; Francesco Cucinelli | Zendy; Salvatore Mancuso | Zendy; Simona Panunzi | Zendy; Andrea De Gaetano | Zendy; Antonio Lanzone | Zendy

Open Access

Assessment of Insulin Sensitivity from Measurements in the Fasting State and during an Oral Glucose Tolerance Test in Polycystic Ovary Syndrome and Menopausal Patients

Author(s) -

Mario Ciampelli,

Fulvio Leoni,

Francesco Cucinelli,

Salvatore Mancuso,

Simona Panunzi,

Andrea De Gaetano,

Antonio Lanzone

Publication year - 2005

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2004-0410

Subject(s) - polycystic ovary , insulin resistance , medicine , endocrinology , receiver operating characteristic , glucose clamp technique , diabetes mellitus , glucose tolerance test , area under the curve , population , quantitative insulin sensitivity check index , insulin , impaired glucose tolerance , pancreatic hormone , insulin sensitivity , environmental health

Polycystic ovary syndrome (PCOS) and menopausal subjects are characterized by an increased cardiovascular and type 2 diabetes mellitus risk, at least partially related to insulin disturbances. The evaluation of insulin resistance in these patients could be useful as primary prevention. The aim of the study was to verify the validity of several indexes of insulin sensitivity in PCOS and menopausal subjects by comparing the data obtained by these indexes to those of euglycemic-hyperinsulinemic clamp studies.

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