MST Kinases and Metabolism | Zendy

Celia M. Pombo | Zendy; Cristina Iglesias | Zendy; Miriam Sartages | Zendy; Juan Zalvide | Zendy

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MST Kinases and Metabolism

Author(s) -

Celia M. Pombo,

Cristina Iglesias,

Miriam Sartages,

Juan Zalvide

Publication year - 2019

Publication title -

endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.674

H-Index - 257

eISSN - 1945-7170

pISSN - 0013-7227

DOI - 10.1210/en.2018-00898

Subject(s) - kinase , function (biology) , metabolism , protein serine threonine kinases , biology , homeostasis , microbiology and biotechnology , bioinformatics , protein kinase a , biochemistry

Since the discovery of the mammalian sterile twenty (MST) kinase family of proteins (MST1/STK4, MST2/STK3, MST3/STK24, and SOK1/STK25), much has been done that adds to our knowledge of their structure, regulation, and function. In the last few years, a series of articles has unveiled a previous unknown relation of these kinases with metabolic regulation and the homeostasis of metabolic tissues. The aim of this review is to bring together this body of data to provide a detailed picture of the current knowledge about these proteins, metabolism, and some of the associated diseases.

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