Minireview: Glucagon in Stress and Energy Homeostasis | Zendy

Ben Jones | Zendy; Tricia Tan | Zendy; Stephen R. Bloom | Zendy

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Minireview: Glucagon in Stress and Energy Homeostasis

Author(s) -

Ben Jones,

Tricia Tan,

Stephen R. Bloom

Publication year - 2012

Publication title -

endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.674

H-Index - 257

eISSN - 1945-7170

pISSN - 0013-7227

DOI - 10.1210/en.2011-1979

Subject(s) - glucagon , endocrinology , medicine , hypoglycemia , glucose homeostasis , hormone , starvation , homeostasis , energy homeostasis , energy expenditure , insulin , receptor , insulin resistance

Glucagon is traditionally thought of as an antihypoglycemic hormone, for example in response to starvation. However, it actually increases energy expenditure and has other actions not in line with protection from hypoglycemia. Furthermore, it is often found to be elevated when glucose is also raised, for example in circumstances of psychological and metabolic stress. These findings seem more in keeping with glucagon having some role as a hormone enhancing the response to stress.

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