Once-Weekly Somapacitan vs Daily GH in Children With GH Deficiency: Results From a Randomized Phase 2 Trial | Zendy

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Open Access

Once-Weekly Somapacitan vs Daily GH in Children With GH Deficiency: Results From a Randomized Phase 2 Trial

Author(s) -

Lars Sävendahl,

Tadej Battelino,

Meryl Brod,

Michael Højby Rasmussen,

Reiko Horikawa,

Rasmus Vestergaard Juul,

Paul Saenger,

REAL study group,

Dieter Furthner,

Bettina Piringer,

Lorenz AuerHackenberg,

Klaus Schmitt,

Marlene Reitmayr,

Marcello D. Bronstein,

Francisco Samuel Magalhães Lima,

Martin Wabitsch,

Carsten Posovszky,

Volker Böttcher,

Alexander Mann,

Eli Hershkovitz,

Alon Haim,

Neta Lowenthal,

Orit Pinhas Hamiel,

Sharon Sheinvald Levin,

Kineret MazorAronovitch,

Michal BenAmi,

Yael Levy Shraga,

Dalit Modan,

Noah Gruber,

Moshe Phillip,

Yael Lebenthal,

Ariel Tenenbaum,

Alon Eliakim,

Nitzan Dror,

Ruby Haviv,

Nehama ZuckermanLevin,

Naim Shehadeh,

Liav Givon,

Ameer Elemy,

Miriam Marji,

Vardit Gepstein,

Praveen V. Pavithran,

Prof.dr. Soedjono Aswin,

Nithiya Abraham,

Rajesh Khadgawat,

Yashdeep Gupta,

Vaman Khadilkar,

Anuradha Khadilkar,

Sagar Lad,

Reiko Horikawa,

Yasuhiro Naiki,

Yasuko Ogiwara,

Yuta Chiba,

Yusuke Fujisawa,

Yumiko Terada,

Tomoko Yoshida,

Kenichi Kinjo,

Atsushi Tsukamura,

Shinobu Ida,

Yuri Etani,

Yasuko Shoji,

Masanobu Kawai,

Hisakazu Nakajima,

Jun Mori,

Shota Fukuhara,

Keiichi Shigehara,

Hidechika Morimoto,

Yusuke Tsuma,

Yasuhiro Kawabe,

Takeshi Ota,

Kenichi Kashimada,

Ryuichi Nakagawa,

Atsumi TsujiHosokawa,

Risa Nomura,

Kei Takasawa,

T Yamauchi,

Kanako Ishii,

Naoko Toda,

Kazuhiro Ohkubo,

Tohru Yorifuji,

Yuki Hosokawa,

Rie Kawakita,

Yukiko Hashimoto,

Azumi Sakakibara,

Shinji Higuchi,

S Soneda,

Kenichiro Ogushi,

Shuichi Yatsuga,

Yasutoshi Koga,

Takako Matsumoto,

Miyuki Kitamura,

Lars Sävendahl,

Ricard Nergårdh,

Tadej Battelino,

Mojca Žerjav Tanšek,

Serap Turan,

Abdullah Bereket,

Zeynep Atay,

Azad Akbarzade,

О.V. Bolshova,

М.D. Тronko,

Olga Vyshnevskaya,

N. A. Sprynchuk,

Iryna Lukashuk,

Natalia Muz,

T. A. Marchenko,

Nataliya Chorna,

Marіana Konovalova,

Liliya Zelinska,

Lawrence A. Silverman,

Barbara Cerame,

Sunita Cheruvu,

Daisy Chin,

Laurie Ebner-Lyon,

Marie Fox,

Marianicolette-Gentile,

Kristin Sabanosh,

Harold Starkman,

I. Howard Marshall,

Mariam Gangat,

Sadana Balachandar,

Philippe Backeljauw,

Andrew Dauber,

Leah Tyzinski,

Paul Saenger,

Luis Zamora Siliezar,

Jacqueline P Velasco,

Judith L. Ross,

Martha Bardsley,

Karen Kowal,

Gad B. Kletter,

Britney G Frazier,

Kathryn Garrison

Publication year - 2020

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/clinem/dgz310

Subject(s) - medicine , randomized controlled trial , endocrinology , pediatrics

Daily growth hormone (GH) injections can be burdensome for patients and carers. Somapacitan is a long-acting, reversible albumin-binding GH derivative in development for once-weekly administration in patients with growth hormone deficiency (GHD).

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