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Opioids and Their Endocrine Effects: A Systematic Review and Meta-analysis
Author(s) -
Friso de Vries,
Mees Bruin,
Daniel J. Lobatto,
Olaf M. Dekkers,
Jan W. Schoones,
Wouter R. van Furth,
Alberto M. Pereira,
Niki Karavitaki,
Nienke R. Biermasz,
Amir H. Zamanipoor Najafabadi
Publication year - 2019
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/clinem/dgz022
Subject(s) - medicine , meta analysis , opioid , context (archaeology) , confidence interval , methadone , endocrine system , endocrinology , hormone , anesthesia , paleontology , receptor , biology
The increased use of opioids has resulted in an unprecedented opioid epidemic. Chronic opioid use causes hypogonadism, but its frequency, as well as the effects of opioids on other hypothalamo-pituitary-end organ hormone axes, remains unclear.

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