Effects of GLP-1 Infusion Upon Whole-body Glucose Uptake and Skeletal Muscle Perfusion During Fed-state in Older Men | Zendy

Haitham Abdulla | Zendy; Bethan E. Phillips | Zendy; Daniel J. Wilkinson | Zendy; Amanda Gates | Zendy; Marie C. Limb | Zendy; Tereza Jandova | Zendy; Joseph J. Bass | Zendy; Johnathan Lewis | Zendy; John P. Williams | Zendy; Kenneth Smith | Zendy; Iskandar Idris | Zendy; Philip J. Atherton | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Effects of GLP-1 Infusion Upon Whole-body Glucose Uptake and Skeletal Muscle Perfusion During Fed-state in Older Men

Author(s) -

Haitham Abdulla,

Bethan E. Phillips,

Daniel J. Wilkinson,

Amanda Gates,

Marie C. Limb,

Tereza Jandova,

Joseph J. Bass,

Johnathan Lewis,

John P. Williams,

Kenneth Smith,

Iskandar Idris,

Philip J. Atherton

Publication year - 2022

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/clinem/dgac613

Subject(s) - postprandial , medicine , endocrinology , insulin , glucose uptake , perfusion , basal (medicine) , skeletal muscle , glycemic , carbohydrate metabolism

Ageing skeletal muscles become both insulin resistant and atrophic. The hormone glucagon-like peptide 1 (GLP-1) facilitates postprandial glucose uptake as well as augmenting muscle perfusion, independent of insulin action. We thus hypothesized exogenous GLP-1 infusions would enhance muscle perfusion and positively affect glucose metabolism during fed-state clamps in older people.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research