Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism | Zendy

Mohamed K.M. Shakir | Zendy; Daniel I. Brooks | Zendy; Elizabeth A. McAninch | Zendy; Tatiana L. Fonseca | Zendy; Q. Vinh | Zendy; Antônio C. Bianco | Zendy; Thanh D. Hoang | Zendy

Open Access

Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism

Author(s) -

Mohamed K.M. Shakir,

Daniel I. Brooks,

Elizabeth A. McAninch,

Tatiana L. Fonseca,

Q. Vinh,

Antônio C. Bianco,

Thanh D. Hoang

Publication year - 2021

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/clinem/dgab478

Subject(s) - levothyroxine , medicine , thyroid , pediatrics , endocrinology

Studies comparing levothyroxine (LT4) therapy with LT4 + liothyronine (LT3) or desiccated thyroid extract (DTE) did not detect consistent superiority of either treatment. Here, we investigated these therapies, focusing on the whole group of LT4-treated hypothyroid patients, while also exploring the most symptomatic patients.

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