z-logo
open-access-imgOpen Access
Genetic Predisposition to Type 2 Diabetes and Insulin Levels Is Positively Associated With Serum Urate Levels
Author(s) -
Jiahao Zhu,
Lingling Sun,
Jing Yang,
Jiayao Fan,
Lap Ah Tse,
Yingjun Li
Publication year - 2021
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/clinem/dgab200
Subject(s) - mendelian randomization , gout , medicine , type 2 diabetes , insulin resistance , odds ratio , glycemic , endocrinology , genetic predisposition , homeostatic model assessment , diabetes mellitus , insulin , uric acid , genotype , biology , genetics , genetic variants , disease , gene
Previous epidemiological evidence showed that type 2 diabetes (T2D) is related with gout. However, the causality and the direction of this association are still not definitely elucidated. We investigated bidirectional associations of T2D and glycemic traits with serum urate concentrations and gout using a Mendelian randomization approach.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom