Investigation of Mechanical, Material, and Compositional Determinants of Human Trabecular Bone Quality in Type 2 Diabetes | Zendy

Praveer Sihota | Zendy; Ram Naresh Yadav | Zendy; Ruban Dhaliwal | Zendy; Jagadeesh Chandra Bose | Zendy; Vandana Dhiman | Zendy; Deepak Neradi | Zendy; Shailesh Karn | Zendy; Sidhartha Sharma | Zendy; Sameer Aggarwal | Zendy; Vijay Goni | Zendy; Vishwajeet Mehandia | Zendy; Deepak Vashishth | Zendy; Sanjay Kumar Bhadada | Zendy; Navin Kumar | Zendy

Open Access

Investigation of Mechanical, Material, and Compositional Determinants of Human Trabecular Bone Quality in Type 2 Diabetes

Author(s) -

Praveer Sihota,

Ram Naresh Yadav,

Ruban Dhaliwal,

Jagadeesh Chandra Bose,

Vandana Dhiman,

Deepak Neradi,

Shailesh Karn,

Sidhartha Sharma,

Sameer Aggarwal,

Vijay Goni,

Vishwajeet Mehandia,

Deepak Vashishth,

Sanjay Kumar Bhadada,

Navin Kumar

Publication year - 2021

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/clinem/dgab027

Subject(s) - bone mineral , diabetes mellitus , context (archaeology) , medicine , type 2 diabetes , bone density , bone tissue , osteoporosis , nanoindentation , bone fracture , endocrinology , dentistry , materials science , anatomy , composite material , biology , paleontology , radiology

Increased bone fragility and reduced energy absorption to fracture associated with type 2 diabetes (T2D) cannot be explained by bone mineral density alone. This study, for the first time, reports on alterations in bone tissue's material properties obtained from individuals with diabetes and known fragility fracture status.

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