Dynamics of Islet Autoantibodies During Prospective Follow-Up From Birth to Age 15 Years
Author(s) -
Petra M Pöllänen,
Samppa Ryhänen,
Jorma Toppari,
Jorma Ilonen,
Paula Vähäsalo,
Riitta Veijola,
Heli Siljander,
Mikael Knip
Publication year - 2020
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/clinem/dgaa624
Subject(s) - autoantibody , seroconversion , type 1 diabetes , medicine , islet , autoimmunity , population , context (archaeology) , immunology , glutamate decarboxylase , endocrinology , diabetes mellitus , insulin , disease , antibody , biology , paleontology , biochemistry , enzyme , environmental health
We set out to characterize the dynamics of islet autoantibodies over the first 15 years of life in children carrying genetic susceptibility to type 1 diabetes (T1D). We also assessed systematically the role of zinc transporter 8 autoantibodies (ZnT8A) in this context.
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