CATS II Long-term Anthropometric and Metabolic Effects of Maternal Sub-optimal Thyroid Function in Offspring and Mothers
Author(s) -
Ilaria Muller,
Peter Taylor,
Rhian Daniel,
C. N. Hales,
A. Scholz,
Toby Candler,
Rebecca Pettit,
W. D. Evans,
Dionne Shillabeer,
Mohd Shazli Draman,
Colin Dayan,
Hiu Tang,
Onyebuchi Okosieme,
John W Gregory,
John H. Lazarus,
Aled Rees,
Marian Ludgate
Publication year - 2020
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/clinem/dgaa129
Subject(s) - medicine , levothyroxine , thyroid function , offspring , endocrinology , body mass index , cats , context (archaeology) , interquartile range , thyroid , adiponectin , pregnancy , obstetrics , obesity , insulin resistance , biology , paleontology , genetics
The Controlled Antenatal Thyroid Screening Study I (CATS-I) was a randomized controlled trial investigating the effects of levothyroxine therapy for suboptimal gestational thyroid function (SGTF), comparing outcomes in children of treated (SGTF-T) with untreated (SGTF-U) women during pregnancy. This follow-up study, CATS-II, reports the long-term effects on anthropometric, bone, and cardiometabolic outcomes in mothers and offspring and includes a group with normal gestational thyroid function (NGTF).
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