Sleep-related breathing disorders : experimental models and therapeutic potential

Overview: pathophysiology of sleep-related breathing disorders in man - unanswered questions. General techniques: instrumentation and methods for chronic studies of sleep and breathing in rodents neurochemical evidence for the cholinergic modulation of sleep and breathing functional anatomical analysis of respiratory circuitry gene and protein expression and regulation in the central nervous system. Experimental sleep-related breathing disorders: intermittent hypoxia computer-controlled airway occlusion. Naturally occurring sleep-related breathing disorders: the pre-term lamb - a unique animal model of neonatal respiratory instability neonatal rat mature rat English bulldog aquatic mammals.