Open AccessOutcomes of Childhood Noninfant Acute Lymphoblastic Leukemia With 11q23/KMT2ARearrangements in a Modern Therapy Era: A Retrospective International Study
Author(s) -
Andishe Attarbaschi,
Anja Möricke,
Christine J. Harrison,
Georg Mann,
André Baruchel,
Barbara De Moerloose,
Valentino Conter,
Meenakshi Devidas,
Sarah Elitzur,
Gabriele Escherich,
Stephen P. Hunger,
Keizo Horibe,
Atsushi Manabe,
Mig L. Loh,
Rob Pieters,
Kjeld Schmiegelow,
Lewis B. Silverman,
Jan Starý,
Ajay Vora,
ChingHon Pui,
Martin Schrappe,
Martin Zimmermann
Publication year - 2023
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.22.01297
Subject(s) - medicine , minimal residual disease , chromosomal translocation , hematopoietic stem cell transplantation , oncology , retrospective cohort study , leukemia , lymphoblastic leukemia , gastroenterology , transplantation , immunology , gene , genetics , biology
We aimed to study prognostic factors and efficacy of allogeneic hematopoietic stem-cell transplantation (allo-HSCT) in first remission of patients with noninfant childhood acute lymphoblastic leukemia (ALL) with 11q23/ KMT2A rearrangements treated with chemotherapy regimens between 1995 and 2010.