High Graft CD8 Cell Dose Predicts Improved Survival and Enables Better Donor Selection in Allogeneic Stem-Cell Transplantation With Reduced-Intensity Conditioning
Author(s) -
Ran Reshef,
Austin P. Huffman,
Amy Gao,
Marlise R. Luskin,
Noelle V. Frey,
Saar Gill,
Elizabeth O. Hexner,
Taku Kambayashi,
Alison W. Loren,
Selina M. Luger,
James K. Mangan,
Sunita D. Nasta,
Lee P. Richman,
Mary Sell,
Edward A. Stadtmauer,
Robert H. Vonderheide,
Rosemarie Mick,
David Porter
Publication year - 2015
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2014.60.1203
Subject(s) - medicine , stem cell , conditioning , transplantation , selection (genetic algorithm) , intensity (physics) , cd8 , oncology , immunology , surgery , immune system , biology , microbiology and biotechnology , statistics , physics , mathematics , quantum mechanics , artificial intelligence , computer science
To characterize the impact of graft T-cell composition on outcomes of reduced-intensity conditioned (RIC) allogeneic hematopoietic stem-cell transplantation (alloHSCT) in adults with hematologic malignancies.
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