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Multiple Biopsies and Detection of Cervical Cancer Precursors at Colposcopy
Author(s) -
Nicolas Wentzensen,
Joan L. Walker,
Michael A. Gold,
Katie Smith,
Rosemary E. Zuna,
Cara Mathews,
S. Terence Dunn,
Roy Zhang,
Katherine Moxley,
Erin Bishop,
Meaghan Tenney,
E. Nugent,
Barry I. Graubard,
Sholom Wacholder,
Mark Schiffman
Publication year - 2014
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2014.55.9948
Subject(s) - colposcopy , medicine , biopsy , cervical cancer , squamous intraepithelial lesion , population , cancer , lesion , gynecology , cervical intraepithelial neoplasia , radiology , pathology , environmental health
Women with abnormal cervical cancer screening results are referred to colposcopy and biopsy for diagnosis of cervical cancer precursors (high-grade squamous intraepithelial lesions [HSILs]). Colposcopy with a single biopsy can miss identification of HSILs. No systematic study has quantified the improved detection of HSIL by taking multiple lesion-directed biopsies.

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