Cabozantinib in Progressive Medullary Thyroid Cancer
Author(s) -
Rossella Elisei,
Martin Schlumberger,
Stefan Müller,
Patrick Schöffski,
Marcia S. Brose,
Manisha H. Shah,
Lisa Licitra,
Barbara Jarząb,
В. С. Медведев,
Michael C. Kreißl,
Bruno Niederle,
Ezra E.W. Cohen,
Lori J. Wirth,
Haythem Ali,
Colin Hessel,
Yifah Yaron,
Douglas W. Ball,
Barry D. Nelkin,
Steven I. Sherman
Publication year - 2013
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2012.48.4659
Subject(s) - cabozantinib , medicine , medullary thyroid cancer , placebo , discontinuation , oncology , tyrosine kinase inhibitor , adverse effect , hazard ratio , cancer , gastroenterology , surgery , thyroid cancer , pathology , confidence interval , alternative medicine
Cabozantinib, a tyrosine kinase inhibitor (TKI) of hepatocyte growth factor receptor (MET), vascular endothelial growth factor receptor 2, and rearranged during transfection (RET), demonstrated clinical activity in patients with medullary thyroid cancer (MTC) in phase I.
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