Chromosomal Abnormalities Are Major Prognostic Factors in Elderly Patients With Multiple Myeloma: The Intergroupe Francophone du Myélome Experience
Author(s) -
Hervé AvetLoiseau,
Cyrille Hulin,
L. Campion,
Philippe Rodon,
Gérald Marit,
Michel Attal,
Bruno Royer,
Mamoun Dib,
Laurent Voillat,
Didier Bouscary,
Denis Caillot,
Marc Wetterwald,
Brigitte Pegourié,
G. Lepeu,
Bernadette Corront,
Lionel Karlin,
AnneMarie Stoppa,
JeanGabriel Fuzibet,
X. Delbrel,
François Guilhot,
Brigitte Kolb,
Olivier Decaux,
Thierry Lamy,
Laurent Garderet,
Olivier Allangba,
François Lifermann,
Bruno Anglaret,
Philippe Moreau,
JeanLuc Harousseau,
Thierry Façon
Publication year - 2013
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2012.46.2598
Subject(s) - medicine , multiple myeloma , chemotherapy , melphalan , incidence (geometry) , prednisone , oncology , surgery , optics , physics
Chromosomal abnormalities, especially t(4;14) and del(17p), are major prognostic factors in patients with multiple myeloma (MM). However, this has been especially demonstrated in patients age < 66 years treated with intensive approaches. The goal of this study was to address this issue in elderly patients treated with conventional-dose chemotherapy.
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