Cytokine Genetic Variations and Fatigue Among Patients With Breast Cancer
Author(s) -
Julienne E. Bower,
Patricia A. Ganz,
Michael R. Irwin,
Steven A. Castellon,
Jesusa M.G. Arevalo,
Steve W. Cole
Publication year - 2013
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2012.46.2143
Subject(s) - medicine , cancer related fatigue , breast cancer , single nucleotide polymorphism , genotyping , allele , cancer , oncology , genotype , gene , genetics , biology
Fatigue is a common adverse effect of cancer treatment and may persist for years after treatment completion. However, risk factors for post-treatment fatigue have not been determined. On the basis of studies suggesting an inflammatory basis for fatigue, this study tested the hypothesis that expression-regulating polymorphisms in proinflammatory cytokine genes would predict post-treatment fatigue in breast cancer survivors.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom