Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: miR-155 Upregulation Independently Identifies High-Risk Patients | Zendy

Guido Marcucci | Zendy; Kati Maharry | Zendy; Klaus H. Metzeler | Zendy; Stefano Volinia | Zendy; Yue-Zhong Wu | Zendy; Krzysztof Mrózek | Zendy; Deedra Nicolet | Zendy; Jessica Kohlschmidt | Zendy; Susan P. Whitman | Zendy; Jason H. Mendler | Zendy; Sebastian Schwind | Zendy; Heiko Becker | Zendy; AnnKathrin Eisfeld | Zendy; Andrew J. Carroll | Zendy; Bayard L. Powell | Zendy; Jonathan E. Kolitz | Zendy; Ramiro Garzon | Zendy; Michael A. Caligiuri | Zendy; Richard M. Stone | Zendy; Clara D. Bloomfield | Zendy

Open Access

Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: miR-155 Upregulation Independently Identifies High-Risk Patients

Author(s) -

Guido Marcucci,

Kati Maharry,

Klaus H. Metzeler,

Stefano Volinia,

Yue-Zhong Wu,

Krzysztof Mrózek,

Deedra Nicolet,

Jessica Kohlschmidt,

Susan P. Whitman,

Jason H. Mendler,

Sebastian Schwind,

Heiko Becker,

AnnKathrin Eisfeld,

Andrew J. Carroll,

Bayard L. Powell,

Jonathan E. Kolitz,

Ramiro Garzon,

Michael A. Caligiuri,

Richard M. Stone,

Clara D. Bloomfield

Publication year - 2013

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.2012.45.6228

Subject(s) - medicine , myeloid leukemia , downregulation and upregulation , microrna , leukemia , cancer research , myeloid , oncology , gene , genetics , biology

To evaluate the impact of miR-155 on the outcome of adults with cytogenetically normal (CN) acute myeloid leukemia (AML) in the context of other clinical and molecular prognosticators and to gain insight into the leukemogenic role of this microRNA.

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