Effect of Ruxolitinib Therapy on Myelofibrosis-Related Symptoms and Other Patient-Reported Outcomes in COMFORT-I: A Randomized, Double-Blind, Placebo-Controlled Trial
Author(s) -
Ruben A. Mesa,
Jason Gotlib,
Vikas Gupta,
John Catalano,
Michael W. Deininger,
Alan L. Shields,
Carole B. Miller,
Richard T. Silver,
Moshe Talpaz,
Elliott F. Winton,
Jimmie H. Harvey,
Thomas Hare,
Susan EricksonViitanen,
William Sun,
Victor Sandor,
Richard S. Levy,
Hagop M. Kantarjian,
Srđan Verstovšek
Publication year - 2013
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2012.44.4489
Subject(s) - ruxolitinib , medicine , myelofibrosis , placebo , quality of life (healthcare) , physical therapy , clinical trial , randomized controlled trial , bone marrow , alternative medicine , pathology , nursing
To assess the effects of ruxolitinib on symptom burden and quality of life (QoL) and to evaluate the ability of the modified Myelofibrosis Symptom Assessment Form (MFSAF) v2.0 to measure meaningful changes in myelofibrosis-related symptoms in patients with myelofibrosis.
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