Randomized Phase III Trial of Induction Chemotherapy With Docetaxel, Cisplatin, and Fluorouracil Followed by Surgery Versus Up-Front Surgery in Locally Advanced Resectable Oral Squamous Cell Carcinoma | Zendy

Lai-ping Zhong | Zendy; Chen-ping Zhang | Zendy; Guo-xin Ren | Zendy; Wei Guo | Zendy; William N. William | Zendy; Jian Sun | Zendy; Han-guang Zhu | Zendy; Wen-yong Tu | Zendy; Jiang LI | Zendy; Yi-li Cai | Zendy; Li-zhen Wang | Zendy; Xin-dong Fan | Zendy; Zhong-he Wang | Zendy; Yong-jie Hu | Zendy; Tong Ji | Zendy; Wen-jun Yang | Zendy; Weimin Ye | Zendy; Jun Li | Zendy; Yue He | Zendy; Yan-an Wang | Zendy; Li-Qun Xu | Zendy; Bo-song Wang | Zendy; Merrill S. Kies | Zendy; J. Jack Lee | Zendy; Jeffrey N. Myers | Zendy; Zhiyuan Zhang | Zendy

Open Access

Randomized Phase III Trial of Induction Chemotherapy With Docetaxel, Cisplatin, and Fluorouracil Followed by Surgery Versus Up-Front Surgery in Locally Advanced Resectable Oral Squamous Cell Carcinoma

Author(s) -

Lai-ping Zhong,

Chen-ping Zhang,

Guo-xin Ren,

Wei Guo,

William N. William,

Jian Sun,

Han-guang Zhu,

Wen-yong Tu,

Jiang LI,

Yi-li Cai,

Li-zhen Wang,

Xin-dong Fan,

Zhong-he Wang,

Yong-jie Hu,

Tong Ji,

Wen-jun Yang,

Weimin Ye,

Jun Li,

Yue He,

Yan-an Wang,

Li-Qun Xu,

Bo-song Wang,

Merrill S. Kies,

J. Jack Lee,

Jeffrey N. Myers,

Zhiyuan Zhang

Publication year - 2012

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.2012.43.8820

Subject(s) - medicine , docetaxel , induction chemotherapy , chemotherapy , surgery , radiation therapy , fluorouracil , perioperative , cisplatin , radical surgery , clinical endpoint , urology , randomized controlled trial , cancer

To evaluate induction chemotherapy with docetaxel, cisplatin, and fluorouracil (TPF) followed by surgery and postoperative radiotherapy versus up-front surgery and postoperative radiotherapy in patients with locally advanced resectable oral squamous cell carcinoma (OSCC).

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