Prognostic Significance of Progesterone Receptor–Positive Tumor Cells Within Immunohistochemically Defined Luminal A Breast Cancer | Zendy

Aleix Prat | Zendy; Maggie C.U. Cheang | Zendy; Miguel Martín | Zendy; Joel S. Parker | Zendy; Eva Carrasco | Zendy; Rosalía Caballero | Zendy; Scott Tyldesley | Zendy; Karen A. Gelmon | Zendy; Philip S. Bernard | Zendy; Torsten O. Nielsen | Zendy; Charles M. Perou | Zendy

Open Access

Prognostic Significance of Progesterone Receptor–Positive Tumor Cells Within Immunohistochemically Defined Luminal A Breast Cancer

Author(s) -

Aleix Prat,

Maggie C.U. Cheang,

Miguel Martín,

Joel S. Parker,

Eva Carrasco,

Rosalía Caballero,

Scott Tyldesley,

Karen A. Gelmon,

Philip S. Bernard,

Torsten O. Nielsen,

Charles M. Perou

Publication year - 2012

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.2012.43.4134

Subject(s) - medicine , immunohistochemistry , progesterone receptor , breast cancer , oncology , tissue microarray , proportional hazards model , cancer , pathology , cancer research , estrogen receptor

Current immunohistochemical (IHC)-based definitions of luminal A and B breast cancers are imperfect when compared with multigene expression-based assays. In this study, we sought to improve the IHC subtyping by examining the pathologic and gene expression characteristics of genomically defined luminal A and B subtypes.

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