Randomized Phase III Study of Gemcitabine Plus S-1, S-1 Alone, or Gemcitabine Alone in Patients With Locally Advanced and Metastatic Pancreatic Cancer in Japan and Taiwan: GEST Study
Author(s) -
Hideki Ueno,
Tatsuya Ioka,
Masafumi Ikeda,
Shinichi Ohkawa,
Hiroaki Yanagimoto,
Narikazu Boku,
Akira Fukutomi,
Kazuya Sugimori,
Hideo Baba,
Kenji Yamao,
T Shimamura,
Masayuki Sho,
Masayuki Kitano,
AnnLii Cheng,
Kazuhiro Mizumoto,
JenShi Chen,
Junji Furuse,
Akihiro Funakoshi,
Takashi Hatori,
Taketo Yamaguchi,
Shinichi Egawa,
Atsushi Satō,
Yasuo Ohashi,
Takuji Okusaka,
Masao Tanaka
Publication year - 2013
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2012.43.3680
Subject(s) - gemcitabine , medicine , hazard ratio , pancreatic cancer , deoxycytidine , chemotherapy , antimetabolite , gastroenterology , oncology , phases of clinical research , cancer , confidence interval
The present phase III study was designed to investigate the noninferiority of S-1 alone and superiority of gemcitabine plus S-1 compared with gemcitabine alone with respect to overall survival.
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