Postinduction Dexamethasone and Individualized Dosing of Escherichia Coli L-Asparaginase Each Improve Outcome of Children and Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia: Results From a Randomized Study—Dana-Farber Cancer Institute ALL Consortium Protocol 00-01 | Zendy

Lynda M. Vrooman | Zendy; Kristen E. Stevenson | Zendy; Jeffrey G. Supko | Zendy; Jane O’Brien | Zendy; Suzanne E. Dahlberg | Zendy; Barbara L. Asselin | Zendy; Uma H. Athale | Zendy; Luis A. Clavell | Zendy; Kara M. Kelly | Zendy; Jeffery L. Kutok | Zendy; Caroline Laverdière | Zendy; Steven E. Lipshultz | Zendy; Bruno Michon | Zendy; Marshall A. Schorin | Zendy; Mary V. Relling | Zendy; Harvey J. Cohen | Zendy; Doneuberg | Zendy; Stephen E. Sallan | Zendy; Lewis B. Silverman | Zendy

Open Access

Postinduction Dexamethasone and Individualized Dosing of Escherichia Coli L-Asparaginase Each Improve Outcome of Children and Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia: Results From a Randomized Study—Dana-Farber Cancer Institute ALL Consortium Protocol 00-01

Author(s) -

Lynda M. Vrooman,

Kristen E. Stevenson,

Jeffrey G. Supko,

Jane O’Brien,

Suzanne E. Dahlberg,

Barbara L. Asselin,

Uma H. Athale,

Luis A. Clavell,

Kara M. Kelly,

Jeffery L. Kutok,

Caroline Laverdière,

Steven E. Lipshultz,

Bruno Michon,

Marshall A. Schorin,

Mary V. Relling,

Harvey J. Cohen,

Doneuberg,

Stephen E. Sallan,

Lewis B. Silverman

Publication year - 2013

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.2012.43.2070

Subject(s) - medicine , dexamethasone , prednisone , asparaginase , dosing , corticosteroid , randomization , gastroenterology , cumulative incidence , toxicity , surgery , randomized controlled trial , pediatrics , leukemia , lymphoblastic leukemia , cohort

We assessed the toxicity and efficacy of dexamethasone and a novel dosing method of Escherichia coli L-asparaginase (EC-Asnase) in children and adolescents with newly diagnosed acute lymphoblastic leukemia (ALL).

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