Comparative Analysis of Different Approaches to Measure Treatment Response in Acute Myeloid Leukemia
Author(s) -
Hiroto Inaba,
Elaine CoustanSmith,
Xueyuan Cao,
Stanley Pounds,
Sheila Shurtleff,
Kathleen Y. Wang,
Susana C. Raimondi,
Mihaela Onciu,
Jeffrey Jacobsen,
Raul C. Ribeiro,
Gary V. Dahl,
W. Paul Bowman,
Jeffrey W. Taub,
Barbara Degar,
Wing Leung,
James R. Downing,
ChingHon Pui,
Jeffrey E. Rubnitz,
Dario Campana
Publication year - 2012
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2011.41.5323
Subject(s) - flow cytometry , minimal residual disease , medicine , myeloid leukemia , bone marrow , leukemia , cytometry , myeloid , acute leukemia , oncology , pathology , immunology
In acute myeloid leukemia (AML), initial treatment response by morphologic analysis of bone marrow predicts long-term outcome. Response can now be assessed by minimal residual disease (MRD) monitoring with flow cytometry or polymerase chain reaction (PCR). We determined the relation among the results of these approaches and their prognostic value.
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