Nomogram to Predict the Benefit of Radiation for Older Patients With Breast Cancer Treated With Conservative Surgery
Author(s) -
Jeffrey M. Albert,
Diane D. Liu,
Yu Shen,
IWen Pan,
YaChen Tina Shih,
Karen E. Hoffman,
Thomas A. Buchholz,
Sharon H. Giordano,
Benjamin D. Smith
Publication year - 2012
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2011.41.0076
Subject(s) - medicine , nomogram , mastectomy , breast cancer , radiation therapy , concordance , proportional hazards model , oncology , multivariate analysis , epidemiology , surgery , cancer
The role of radiation therapy (RT) after conservative surgery (CS) remains controversial for older patients with breast cancer. Guidelines based on recent clinical trials have suggested that RT may be omitted in selected patients with favorable disease. However, it is not known whether this recommendation should extend to other older women. Accordingly, we developed a nomogram to predict the likelihood of long-term breast preservation with and without RT.
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